Stress echocardiography (SE) has gained recognition as a non-invasive diagnostic imaging modality to assess patients with suspected chronic coronary syndrome (CCS). Since exercise SE was introduced in the 1970s, the widened spectrum of stressors such as inodilators (dobutamine) or vasodilators (adenosine, dipyridamole, and recently regadenoson) continues to be rolled out to patients who are otherwise unsuitable for treadmill or supine bicycle ergometer exercise. The last three decades of advancement of ultrasound technology including transducer and software technology, iterative image reconstruction, and the development of ultrasound enhanced agents led to significant improvement of ultrasound image quality and accurate detection of inducible regional wall motion abnormalities (RWMA).
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