State of the art review: echocardiography based Angina diagnosis

In this paper we are discussing the currently available tools in the diagnosis of angina with non-occlusive coronary artery disease (ANOCA) a potentially disabling condition that affects approximately 30–60% of patients with angina. With the advancement in ultrasound technology, multi-parametric stress echocardiography in combination with hyperventilation provocation echocardiography lends itself as a bedside, scalable, safe … Read more

Summary slide from ESC

As you can see from the summary slide image, the TCRG participated as an invited Faculty in Chairing moderated ports sessions and as an invited expert to the panel discussion at the INOCA International symposium.

Controlled Hyperventilation using Navigator Software

I am delighted to share our latest publication in European Heart Journal – Imaging Methods and Practice. This feasibility study in healthy volunteers evaluates whether our newly developed Ventilation Navigator software application, created in collaboration with Cranfield University, can deliver controlled ventilation by measuring end-tidal CO2 against capillary blood gas values, including CO2 and pH. This proof-of-concept work is an important step towards implementing controlled hyperventilation to assess coronary vasoreactivity in patients with angina … Read more

Situational Syncope Across Diverse Triggers

While transient loss of consciousness is a frequent and alarming clinical presentation, situational syncope—a subtype of neurally mediated reflex syncope—frequently slips under the diagnostic radar. This illuminating case series follows six adults whose fainting or near-fainting spells were triggered by everyday activities ranging from the common, like coughing and micturition, to the highly unusual, including … Read more

Effect of Rate-Controlling Medication on Dobutamine Stress Echocardiography

For years, professional guidelines and expert opinions have conflicted on a crucial pre-test instruction: should patients stop taking their rate-controlling medications (RCMx), like beta-blockers, 48 hours before undergoing a stress echocardiography? While conventional wisdom suggests halting these medications improves diagnostic accuracy by making it easier to reach target heart rates, hard evidence has been strikingly … Read more

Early Prediction of Heart Failure From Routine Cardiac CT

This groundbreaking study reveals how AI can predict heart failure years before symptoms appear by analyzing routine cardiac CT scans. Using advanced “radiomic phenotyping,” researchers have developed a way to detect microscopic changes in the fat surrounding the heart—essentially turning a standard medical image into a powerful early-warning system. Validated with data from over 70,000 … Read more

TCRG Receives Generous Support from MK Friends Charity

We are delighted to announce that the Translational Cardiovascular Research Group (TCRG) has been awarded a generous donation from the MK Friends charity. For over 45 years, MK Friends has been a cornerstone of the Milton Keynes University Hospital community. This latest contribution represents a significant investment in the future of local cardiovascular health. The … Read more