Situational Syncope Across Diverse Triggers

While transient loss of consciousness is a frequent and alarming clinical presentation, situational syncope—a subtype of neurally mediated reflex syncope—frequently slips under the diagnostic radar. This illuminating case series follows six adults whose fainting or near-fainting spells were triggered by everyday activities ranging from the common, like coughing and micturition, to the highly unusual, including … Read more

Effect of Rate-Controlling Medication on Dobutamine Stress Echocardiography

For years, professional guidelines and expert opinions have conflicted on a crucial pre-test instruction: should patients stop taking their rate-controlling medications (RCMx), like beta-blockers, 48 hours before undergoing a stress echocardiography? While conventional wisdom suggests halting these medications improves diagnostic accuracy by making it easier to reach target heart rates, hard evidence has been strikingly … Read more

Diagnostic and Prognostic Performance of Pericoronary Adipose Tissue Attenuation

With great pride we are attaching our Cardiovascular research group’s current research publication as part of the RAPID CTCA trial between 2017-2019 . This trial recruited intermediate risk ACS patients and randomised for CCTA guided and standard clinical care arm. In the  subgroup analysis it show the non superior value of the peri-coronary artery adipose tissue c/w … Read more

Non-invasive cardiovascular and vital signs monitoring techniques

Please find this excellent piece of work from our joint PhD student Qi Yong (Cranfield University – MKUH TCRG.org.uk) entitled: Non-invasive cardiovascular and vital signs monitoring techniques, as a systematic review of emerging contactless cardiovascular monitoring techniques.   This article compares radar-based methods, optical measurements, ballistocardiograph, contactless electrocardiogram (ECG), and wearable devices across eight key dimensions.  The co-autors are: (Prof … Read more

Recent visit to TCRG by Chair of MKUH

We are pleased to communicate that the Chair of our Hospital has visited the Research Group (TCRG) on 29 October. The Chair had a tour of Cardiology and sat down with the researchers who represented our Research team at the European Society of Cardiology Annual meeting in Madrid. The two poster presentations were discussed that … Read more

Long-term Prognostic Value of Myocardial Perfusion Scintigraphy

This study systematically evaluated the long-term outcomes of myocardial perfusion scintigraphy (MPS) in patients with suspected coronary artery disease (CAD). ​ It analysed data from four trials involving 1764 patients with a median follow-up of 35.7 months. ​ Positive MPS results, indicating reversible perfusion defects, were linked to higher risks of major adverse cardiovascular events … Read more

Cautionary Tale of Failed Mitral Valve Replacements

This case report discusses the tragic outcome of a young female patient in her early 50s with rheumatic heart disease (RHD) who underwent multiple mitral valve replacements. Initially diagnosed with mitral valve prolapse at age 12, she received a bioprosthetic mitral valve replacement (bMVR) 26 years later, which degenerated after 13 years, leading to severe … Read more

Four Faces of Infective Endocarditis

Infective endocarditis (IE) remains a formidable clinical challenge. It affects 3–10 peopleper 100,000 annually, with a 30-day mortality rate of up to 30%. The incidence of IEhas risen due to advancements in cardiac care, including the increased use of intra-cardiacelectronic devices (CIEDs) and interventions for structural heart disease. The InternationalCardiology Societies underscore the importance of … Read more